Programme
Joint I International Monothematic Conference on Cholangiocarcinoma
May 4-6 2016, San Sebastian, Spain
ORGANISING COMMITTEE
Jesus M Banales, Spain
Luis Bujanda, Spain
DAY 1 – WEDNESDAY, MAY 4, 2016
16:00 – 19:00 Registration |
18:00 – 18:15 Welcome and introductory remarks Dr. Jesus M. Banales (Spain) Dr. Domenico Alvaro (Italy) Dr. Luis Bujanda (Spain) |
18:15 – 19:00 The pathobiology of biliary epithelia (State of Art Lecture) Dr. Nicholas F. LaRusso (USA) |
19:00 – 22:00 Reception and social gathering |
DAY 2 – THURSDAY, MAY 5, 2016
Cholangiocarcinoma (CCA): general features
Chairs: Dr. Marco Marzioni (Italy) Dr. Michael Trauner (Austria)
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09:00 – 09:20 Classifications, risk factors and clinical features Dr. Domenico Alvaro (Italy) |
09:20 – 09:40 CCA: radiology Dr. Marco Rengo (Italy) |
09:40 – 10:00 Molecular classification of CCA Dr. Jesper Andersen (Denmark) |
New methods for diagnosis
Chairs: Dr. Gianfranco Alpini (USA) Dr. Marcin Krawczyk (Germany/Poland)
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10:00 – 10:20 Biomarkers of CCA in serum and bile: role of extracellular vesicles, miRNAs and beyond Dr. Jesus M. Banales (Sapin) |
10:20 – 10:40 Early detection of CCA – the potential of DNA methylation biomarkers Dr. Guro Lind (Norway) |
10:40 – 11:10 Coffe break |
Cells of origin
Chairs: Dr. Nicholas F. LaRusso (USA) Dr. Guro Lind (Norway)
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11:10 – 11:30 The biliary tree: a reservoir of multipotent stem cells Dr. Lola Reid (USA) |
11:30 – 11:50 Biliarytree stem cell niches and their relevance to histo-pathological features of CCA Dr. Guido Carpino (Italy) |
11:50 – 12:10 Cells of origin and cancer stem cells Dr. Vicenzo Cardinale (Italy) |
Genetics and epigenetics
Chair: Dr. Laura Fouassier (France) Dr. Jesper Andersen (Denmark)
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12:10 – 12:30 Genetic modifiers of the biliary cancer risk Dr. Marcin Krawczyk (Germany/Poland) |
12:30 – 12:50 FGFR fusion genes in intrahepatic CCA Dr. Lewis Roberts (USA) |
12:50 – 14:30 Lunch Break |
Molecular pathways and interactions
Chairs: Dr. Trine Folseraas (Norway) Dr. Jose J.G. Marin (Spain)
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14:30 – 14:50 Activation and failure of the regulation of cholangiocyte proliferation Dr. Marco Marzioni (Italy) |
14:50 – 15:10 Regulation of CCA growth by clock genes Dr. Gianfranco Alpini (USA) |
15:10 – 15:30 Biology of epidermal growth factor receptor in CCA Dr. Laura Fouassier (France) |
15:30 – 15:50 Biology of IL-6 type cytokines in CCA Dr. Andreas Geier/ Dr. Heike Hermanns (Germany) |
15:50 – 16:10 Notch signaling in CCA Dr. Mario Strazzabosco (Italy) |
16:10 – 16:30 Wnt signaling in CCA Dr. Stuart Forbes (UK) |
16:30 – 16:50 Mouse models of CCA Dr. Diego Calvisi (Germany) |
16:50 – 17:10 Coffee break |
General meeting of the members of the ENS-CCA
Chairs: Dr. Jesus M. Banales (Spain) Dr. Domenico Alvaro (Italy) Dr. Jesper Andersen (Denmark)
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17:10 – 18:30 ENS-CCA members meeting |
20:00 – 23:00 Social gathering |
DAY 3 – FRIDAY, MAY 6, 2016
Oral communications (Part I)
Chair: Dr. Joachim C. Mertens (Switzerland) Dr. Luca Fabris (Italy)
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08:00 – 08:20 TBD |
08:20 – 08:40 TBD |
08:40 – 09:00 TBD |
09:00 – 09:20 TBD |
Oral communications (Part II)
Chairs: Dr. Andreas Geier (Germany) Dr. Diego Calvisi (Germany)
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09:20 – 09:40 TBD |
09:40 – 10:00 TBD |
10:00 – 10:20 TBD |
10:20 – 10:40 TBD |
10:40 – 11:10 Coffee break |
Tumor microenvironment
Chair: Dr. Lola Reid (USA) Dr. Guido Carpino (Italy)
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11:10 – 11:30 Tumor stroma in CCA Dr. Joachim C. Mertens (Switzerland) |
11:30 – 11:50 Role of tumor-stroma in CCA invasiveness Dr. Luca Fabris (Italy) |
11:50 – 12:10 Immune microenvironment and CCA Dr. Chiara Raggi (Italy) |
Targeted therapies
Chairs: Dr. Lewis Roberts (USA) Dr. Vicenzo Cardinale (Italy)
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12:10 – 12:30 Plasma membrane transporters: biomarkers and molecular targets in cholangiocarcinoma Dr. Jose J.G. Marin (Spain) |
12:30 – 12:50 The primary cilium as a therapeutic target in carcinogenesis Dr. Sergio Gradilone (USA) |
12:50 – 13:10 PSC – associated CCA – diagnostic challenges and treatment strategies Dr. Trine Folseraas (Norway) |
13:10 – 13:30 norUDCA in context of cholangiopathies Dr. Michael Trauner (Austria) |
13:30 – 13:45 Conclusing remarks Dr. Jesus M. Banales (Spain) Dr. Marco Marzioni (Italy) Dr. Luis Bujanda (Spain) |
14:00 – 17:00 Lunch |